Chloe, Ethan, Iris, John, Jasper and Laila set sail on a ferry for a vacation on a jungle-covered island. Chloe claims she has "seen what happens here" — in her previous life, her boyfriend Ethan tied her up in the woods and left her to the snakes, and she has been reborn before they ever set foot on the island. She warns the group that the island is home to a Mutant Giant Anaconda, but is met with nothing but ridicule. After docking, Chloe finds a huge shed skin near the camp and, drawing on her memory, locates the Underground Shelter beneath the Abandoned Cabin in the backyard. With Jasper and Laila, she fortifies it with Realgar Powder, Mugwort and tin-can trip-wire alarms. Refusing to believe her, Ethan and Iris throw a party with loud music outside the Main Lodge, luring the Giant Anaconda and the snake swarm toward the camp. John is bitten by a venomous snake and abandoned by Ethan, dying in the snake swarm; at the Signal Tower, Ethan and Iris betray each other and both are swallowed by the Giant Anaconda. Guided by the Island Keeper's Log, Chloe's group finds the abandoned Signal Tower outside the Geothermal Cave, repairs the radio, and transmits their coordinates and distress call just before the Giant Anaconda breaks out of the cave. The snake coils against the tower, and Chloe and her companions use a thick rope to harness the snake's own strength, wounding it and driving it back. A rescue ship on the open sea picks up the signal and steers toward the island; the th