After seven hundred years of slumber, vampire Queen Isabella awakens in the body of her descendant and sets out to revive the declining Castan family. Her former subordinate Malcolm colludes with the villain Astor, repeatedly plotting schemes and poison traps, attempting to seize the vampire's supreme treasure and annex the family's power. Relying on her mighty bloodline and wisdom, Isabella defuses crises time and again and uncovers the mastermind behind the scenes. She unites her clansmen to fight against the city-wide blood sacrifice formation, turns the curse inside her body into armor, and finally puts an end to Astor's conspiracy with her own hands. After countless fierce battles, Isabella protects her family and the entire vampire race, carrying on the eternal legend of the vampire queen.
