Xu Nanxing and Shen Yanzhi were once a poor but loving couple, both suffering from Becker's syndrome. At their simple wedding, Xu Nanxing vowed never to betray her, while Shen Yanzhi silently supported her in achieving her dreams. Five years later, Xu Nanxing became the president of Jiuyuan Pharmaceutical. However, due to the careful manipulation of her business partner Yun Ye and Xu Nanxing's negligence, Shen Yanzhi mistakenly believed that Xu Nanxing had changed his heart, and was even unintentionally abandoned by him when he was critically ill on a plane. Heartbroken, he signed a divorce agreement and chose to take medication with unknown side effects to seek complete liberation. When Xu Nanxing finally realized his mistake and tried everything to win her back, Shen Yanzhi's appearance had drastically changed due to the medication, and she had vanished. Filled with remorse, Xu Nanxing searched desperately, staging an extreme "chasing after her husband" drama, only to ultimately miss the unrecognizable Shen Yanzhi, never to find her former love again.