Seraphina Shaw, the underachiever of the Villain Clan, is determined to cultivate cold-resistant mosquitoes to boost her performance. She travels across worlds to find the genius biologist Julian Sutton. The two go from a bizarre collaboration to a sweet romance. With the help of mosquitoes, Seraphina makes a comeback on the villain leaderboard, achieving success in both her career and love life. The entire story is goofy and sweet.