Chloe Clark goes on vacation to the Forest Resort Villa with her bestie and boyfriend. She dreams of being betrayed by them and that everyone will be devoured by a Giant Python. She dismisses it as a nightmare, but the dream turns out to be a prophecy. Chloe Clark warns everyone, but no one believes her. She alone prepares the basement. When the Giant Python attacks, those who trusted her survive in the basement, while her cheating boyfriend and bestie suffer.