Han Li possesses the ultimate magic box that can extract and release diseases. At the pleading of the Liu family, he enters the world to save people, but in Yun City, he is bullied by Huang Zhiming, who wants to take Han Li's magic box for himself. Han Li retaliates against these ungrateful people, but just then, a plague breaks out in Yun City. Han Li ascends to immortality through tribulation, clears away the plague, and saves the people.
