The modern medical genius Dr. Graham unexpectedly dies and finds herself reincarnated in another dynasty as Emily Graham, the eldest daughter of the Graham family. The emperor decrees that the young lady of the Graham family must marry the hot-tempered Prince Rui, Leo Brown. Emily Graham's father, unwilling to let his beloved second daughter, Jessica Graham, marry Leo Brown, forces Emily Graham to marry the prince instead. Emily reveals that Leo Brown has been poisoned with a rare toxin, one that only a few can endure, and the antidote is extremely complicated. However, she offers to cure him, with the condition that he doesn't kill her. After a year, they can divorce. Leo Brown agrees.
