Princess Mia of the bloodline, who had slept for a thousand years, was awakened by a single drop of blood and possessed the body of a human doctor named Mia who had died in a fall. Returning to Boston's Ciyen Hospital, she discovered that her original host had been murdered by her colleague Sophie and her ex-boyfriend Victor, while her research findings had also been stolen. Using her vampiric senses and the medical knowledge of the original Mia, she repeatedly thwarted medical accident traps set by her enemies during surgeries, all while secretly gathering evidence. With covert help from her vampire lover Evan, she exposed Sophie’s academic fraud, Victor’s financial corruption, and Rodriquez’s cover-up. In the end, Sophie fell to her death, Victor was imprisoned, Mia reclaimed her honor and became chief of cardiothoracic surgery, walking hand-in-hand with Evan into a new life.